Lizzie Devine is the love interest of Nigel Uno a.k.a. Numbuh 1 from Codename Kids Next Door. She is very demanding and sometimes threatening. She has a huge crush on Numbuh 1. She first met Numbuh 1 in Operation: L.I.Z.Z.I.E. and used a mind control helmet to make him stay with her instead of the Kids Next Door. In Operation: D.A.T.E., she had earned the temporary position as Numbuh 49. After Numbuh 1 hurts her feelings and the Delightful Children From Down The Lane mind controlled all the party guests and Numbuh 1 and the Kids Next Door had to free all the party guests, Lizzie confronts Numbuh 1 and tries to throw punch at him as he jumped out of the way and allowed the mansion to be destroyed as she and Numbuh 1 hold hands as Numbuh 1 begins to have romantic feelings for Lizzie. However, their relationship didn't go well, in Operation: G.I.R.L.F.R.I.E.N.D., Lizzie breaks up with Numbuh 1 after he leaves her several times during their date. She didn't appear in Operation: T.R.E.A.T.Y., but she was last mentioned by Numbuh 3.